P53 expression in ischemic rat models after the administration of ketamine and ketamine-xylazine

Comparison of Caudal Epidural Administration of Lidocaine and Xylazine to Xylazine/Ketamine Combination in Donkey (Equus asinus)

Objective- Evaulation of analgesic and sedative characteristics of xylazine/ketaminecombination for caudal epidural analgesia in comparison with two routine agents in donkey.Design- Cross over study.Animals- Five healthy adult donkeys of both sexes with body weights ranging from 150-200 kg.Procedures- Three treatments [lidocaine HCl 2% (0.22 mg kg^-1), xylazine HCl 2% (0.17 mg kg^-1) and xylazi...

Evaluation of isoflurane anesthesia after xylazine/ketamine administration in dromedary camels

Effect of Intraarticular Ketamine Administration on the Histopathological Changes of Knee Joint in the Rat Model

Objective- Postoperative pain management in patients that undergone arthroscopy is one of the most important procedures for their rehabilitation. Analgesic injection intra-articularly can facilitate pain control in such patients. The aim of this study was to evaluate the effects of ketamine on articular cartilage in rat model. Design- Experimental study. Animals- Twenty Wistar Rats Procedure...

Comparative evaluation of clinical efficiency of intramuscular diazepam-ketamine, medetomidine-ketamine, and xylazine-ketamine anaesthesia in Ring-necked pheasants (Phasianus colchicus)

Background: Several injectable anaesthetics and sedatives are used in various avian species for general anaesthesia. Birds are very sensitive animals and any mismanagement in a crisis can lead to immediate shock and death. Therefore, careful selection of the safest possible anaesthetic agent and dose is very important. Aims: The aim of this study was to examine...

Ketamine/Xylazine-Induced Corneal Damage in Mice

PURPOSE We have observed that the commonly used ketamine/xylazine anesthesia mix can induce a focally severe and permanent corneal opacity. The purpose of this study was to establish the clinical and histological features of this deleterious side effect, its sensitivity with respect to age and anesthesia protocol, and approaches for avoiding it. METHODS Young C57BL/6J, C57BLKS/J, and SJL/J mi...